ENHANCING CHEMOIMMUNOTHERAPY FOR COLORECTAL CANCER WITH PACLITAXEL AND ALANTOLACTONE VIA CD44-TARGETED NANOPARTICLES: A STAT3 SIGNALING PATHWAY MODULATION APPROACH

Enhancing chemoimmunotherapy for colorectal cancer with paclitaxel and alantolactone via CD44-Targeted nanoparticles: A STAT3 signaling pathway modulation approach

Chemoimmunotherapy has the potential to enhance chemotherapy and modulate Shot glass set the immunosuppressive tumor microenvironment by activating immunogenic cell death (ICD), making it a promising strategy for clinical application.Alantolactone (A) was found to augment the anticancer efficacy of paclitaxel (P) at a molar ratio of 1:0.5 (P:A) thr

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Arrhythmogenic Potential of Myocardial Edema: The Interstitial Osmolality Induces Spiral Waves and Multiple Excitation Wavelets

Myocardial edema is a common symptom of pathological processes in the heart, causing aggravation of cardiovascular diseases and leading to irreversible myocardial remodeling.Patient-based studies show that myocardial edema is associated with arrhythmias.Currently, there are no studies that have examined how Miele G4263Vi Full-Size Integrated Dishwa

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Sherd Shatter Patterns Experiment

In Cloth Dripper field archaeology, the importance of non-diagnostic sherds is often overlooked.This archaeological experiment suggests that archaeologists should take into greater consideration, contexts where sherds are found grouped together in close proximity.The authors tested a series of experimental drops of modern pots which were treated as

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Contribution of immune cells to bone metastasis pathogenesis

Bone metastasis Shot glass set is closely related to the survival rate of cancer patients and reduces their quality of life.The bone marrow microenvironment contains a complex immune cell component with a local microenvironment that is conducive to tumor formation and growth.In this unique immune environment, a variety of immune cells, including T

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